Chronic Fatigue Syndrome Rates High in Childhood Cancer Survivors


Chronic fatigue syndrome has a 3-times greater prevalence among adult survivors of childhood cancers than in the general population. These results were recently published in the Journal of Adolescent and Young Adult Oncology.

Researchers recently conducted a clinical study to evaluate the prevalence of chronic fatigue syndrome (CFS) among adult survivors of childhood cancer; a group of the population in which CFS is not well-studied.

The study included 143 males and 147 females who were childhood leukemia or lymphoma survivors.

The prevalence of CFS among childhood cancer survivors was 27%, compared to the normal approximate 8% of the general population.
The researchers concluded that CFS is increased by approximately 3-times that of the general population among childhood cancer survivors. The authors stated that “a persistent low-grade inflammatory response may be involved in the pathogenesis of CFS.”

Reference: Hamre H, Zeller B, Kanellopoulos A, et al. High prevalence of chronic fatigue in adult long-term survivors of acute lymphoblastic leukemia and lymphoma during childhood and adolescence. Journal of Adolescent and Young Adult Oncology. 2013; 2(1): 2-9.